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  • Writer's pictureLa petite Sirène

Opinion column in the Wall Street Journal by the Franco-Belgian members of OPS

Youth Gender Transition Is Pushed Without Evidence Psychotherapy, not hormones and surgery, is increasingly the first line of treatment abroad

13 juillet 2023 " As experienced professionals involved in direct care for the rapidly growing numbers of gender-diverse youth, the evaluation of medical evidence or both, we were surprised by the Endocrine Society’s claims about the state of evidence for gender-affirming care for youth (Letters, July 5). Stephen Hammes, president of the Endocrine Society, writes, “More than 2,000 studies published since 1975 form a clear picture: Gender-affirming care improves the well-being of transgender and gender-diverse people and reduces the risk of suicide.” This claim is not supported by the best available evidence.

Every systematic review of evidence to date, including one published in the Journal of the Endocrine Society, has found the evidence for mental-health benefits of hormonal interventions for minors to be of low or very low certainty. By contrast, the risks are significant and include sterility, lifelong dependence on medication and the anguish of regret. For this reason, more and more European countries and international professional organizations now recommend psychotherapy rather than hormones and surgeries as the first line of treatment for gender-dysphoric youth..."

This letter is signed by 21 clinicians and researchers from nine countries.


Prof. Riittakerttu Kaltiala, M.D., Ph.D.

Tampere University

Laura Takala, M.D., Ph.D.

Chief Psychiatrist, Alkupsykiatria Clinic


Prof. Richard Byng, M.B.B.Ch., Ph.D.

University of Plymouth

Anna Hutchinson, D.Clin.Psych.

Clinical psychologist, The Integrated Psychology Clinic

Anastassis Spiliadis, Ph.D.(c)

Director, ICF Consultations


Angela Sämfjord, M.D.

Senior consultant, Sahlgrenska University Hospital

Sven Román, M.D.

Child and Adolescent Psychiatrist


Anne Wæhre, M.D., Ph.D.

Senior consultant, Oslo University Hospital


Em. Prof. Patrik Vankrunkelsven, M.D. Ph.D.

Katholieke Universiteit Leuven

Honorary senator

Sophie Dechêne, M.R.C.Psych.

Child and adolescent psychiatrist

Beryl Koener, M.D., Ph.D.

Child and adolescent psychiatrist


Prof. Celine Masson, Ph.D.

Picardy Jules Verne University

Psychologist, Oeuvre de Secours aux Enfants

Co-director, Observatory La Petite Sirène

Caroline Eliacheff, M.D.

Child and adolescent psychiatrist

Co-director, Observatory La Petite Sirène

Em. Prof. Maurice Berger, M.D. Ph.D.

Child psychiatrist


Daniel Halpérin, M.D.



Prof. Reitze Rodseth, Ph.D.

University of Kwazulu-Natal

Janet Giddy, M.B.Ch.B., M.P.H.

Family physician and public-health expert

Allan Donkin, M.B.Ch.B.

Family physician


Clin. Prof. Stephen B. Levine, M.D.

Case Western Reserve University

Clin. Prof. William Malone, M.D.

Idaho College of Osteopathic Medicine

Director, Society for Evidence Based Gender Medicine

Prof. Patrick K. Hunter, M.D.

Florida State University

Pediatrician and bioethicist

Transgenderism has been highly politicized—on both sides. There are those who will justify any hormonal-replacement intervention for any young person who may have been identified as possibly having gender dysphoria. This is dangerous, as probably only a minority of those so identified truly qualify for this diagnosis. On the other hand, there are those who wouldn’t accept any hormonal intervention, regardless of the specifics of the individual patients.

Endocrinologists aren’t psychiatrists. We aren’t the ones who can identify gender-dysphoric individuals. The point isn’t to open the floodgates and offer an often-irreversible treatment to all people who may have issues with their sexuality, but to determine who would truly benefit from it.

Jesus L. Penabad, M.D.

Tarpon Springs, Fla.


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